Sildenafil, the active ingredient in Viagra, is one of several ED pills that’s considered a PDE5 inhibitor. When this enzyme is inhibited, it maximizes the effect of nitric oxide in your body. (That’s important, because your body naturally releases this gas when you’re sexually aroused. So it’s key to the process of getting and maintaining an erection.)
With more nitric oxide in play, the muscles around your penis can relax. In turn, blood flow to your penis improves. And it becomes easier to hold onto your erection, so you can enjoy a sexual encounter.
Sildenafil also works quickly. You can take our chewable Sildenafil tablets—only available on bluechew.com—about one hour before sex. Avoid taking food with your ED pills, especially fatty meals, since they can impact your body’s ability to absorb the drug.
When taken according to directions, the medication is fast-acting, reaching its peak concentration in your bloodstream about one hour after dosing. Then, the medication stays in your body for up to six hours, so you can enjoy a great night with that special someone.
idespread use of sildenafil as treatment for erectile dysfunctionSildenafil is sometimes used to treat men with difficulty achieving and maintaining an erection. For ages 17 and 18, it’s one of several ED pills that’s considered a PDE5 inhibitor.
Now, however, sildenafil is now being studied more for its effectiveness in treating ED. And, because that’s when it comes to ED treatment, the FDA is poised to start using that same FDA-approach next year to treat that age group. “As of early 2015, Pfizer’s FDA-approved ED treatment is sildenafil,” says Dr. Hee-Hb Guo, the medical director of the divisional office of male sexual health at the University of Virginia.
Guo’s study involved more than 300 men ages 18 to 40 who were sexually aroused. The men were randomly assigned to take Viagra or a placebo before sex. The men took Viagra 30 or 60 minutes before sexual activity. Then they took a pill of either sildenafil or the placebo, and the man was helped by the pill for four hours.
After the four-hour period, the man who took the sildenafil tablet began to have an erection that was better for him compared with the man who took the placebo. (The men who took the sildenafil tablet were more likely to have a firm, long-term relationship with their healthcare provider, which can help improve their overall health and sexual function.)
Similarly, the man who took the placebo reported better results with regard to erections that day, Guo says. Specifically, he reported faster results with the sildenafil tablet. “In terms of sexual performance, the sildenafil tablet was faster—30 minutes to 1 hour faster—on average,” he says.
After the four-hour period, the man who took the sildenafil tablet reported that he had an erection that was better for him compared with that he could have had if he took the placebo.
As of early 2015, Pfizer’s FDA-approved ED treatment is sildenafil, which means it’s a PDE5 inhibitor. (Sildenafil is a type of PDE5 inhibitor called a PDE5 inhibitor.) “It maximizes the effect of nitric oxide in your body,” Guo says.
Because sildenafil works more quickly, it can be taken with or without food. Because that means that it’s usually low-fat, low-dose therapy, Guo says, you can take it with or without food.
That’s important because taking sildenafil without a doctor’s advice can lead to side effects that are more likely to happen if you’re taking it with a meal. For example, can can increase your risk of developing:
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Show moreSildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.
Sildenafil is available in 25mg, 50mg, and 100mg strengths.
Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.
Common side effects include:
Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.
Sildenafil should not be used by those:
Inform your doctor of all medications and supplements before use. Interactions may occur with:
Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.
Sildenafil is available by prescription only in the UK.
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